MOUTHWASH NEDENTO · TRICLOSAN
Triclosan, Vitamin B5, Allantoin, Sodium Fluoride.
TOOTHPASTE NEDENTO · TRICLOSAN
Triclosan, Vitamin B5, Allantoin, Sodium Fluoride, Aloe Vera
PHARMACEUTICAL DOSAGE FORM AND FORMULATION.
MOUTHRINSE NEDENTO · TRICLOSAN Triclosan (DCI) 0.15%, Vitamin B5 (DCI) 1.0g, Sodium Fluoride 0.05g, Allantoin 0.2 g, Bioadhesive excipient plus
TOOTHPASTE NEDENTO · TRICLOSAN: Triclosan (DCI) 0.30%, Vitamin B5 (DCI) 1.0g, Sodium fluoride 0.32g, Allantoin 0.2g, Aloe Vera 0.1 g, Bioadhesive excipient plus
THERAPEUTICAL INDICATION: MOUTHRINSE NEDENTO · TRICLOSAN and TOOTHPASTE NEDENTO are products indicated for the treatment of gingivitis. Oral hygiene for prevention and control of bacterial plaque and dental caries. Periodontal disease control in maintenance phase. Bacterial plaque control during orthodontic treatment. Therapeutic effect: Bacterial plaque has been implicated in the origin and development of periodontal diseases. The most common is gingivitis, this is characterized by inflamed and bleeding gums. Chronically established gingivitis can evolve into periodontitis, characterized by a loss of tooth insertion site.
MOUTHRINSE NEDENTO · TRICLOSAN and TOOTHPASTE NEDENTO · TRICLOSAN. are products for oral use formulated to control and prevent gingivitis and dental caries. Its specific formula is based on Triclosan, an efficient antiplaque agent for the maintenance of gingival health, and sodium fluoride, a dental caries inhibiting agent of maximal activity. Due to its Vitamin B5 content and the soothing and regenerative properties of Allantoin, it aids in the reduction of gingivitis damaged gums, keeping them in a good state in combination with an adequate toothbrush and brushing technique.
PHARMACOKINETICS AND PHARMACODYNAMICS:
Pharmacodynamics: The compound has a biocidal activity, provoking proteic or lypoproteic wall lysis of multi-layered membrane and cytoplasm, thus penetrating and interrupting biochemical reactions that support the microorganism’s life; at lower doses it has a bacteriostatic effect. Pharmacokinetics: It is not absorbed by the gastrointestinal tract and it is eliminated through the feces.
CONTRAINDICATIONS: Do not administer to patients allergic to any of the components in the formula.
GENERAL SAFETY PRECAUTIONS: Do not ingest. Keep away from children’s reach. Do not administer during pregnancy and breastfeeding. Restrictions during pregnancy and breastfeeding: Although there are no laboratory reports proving the product to have mutagenic or carcinogenic or having any effect on fetal development or on newborns, this product should not be administered during pregnancy or breastfeeding.
SIDE EFFECTS OR ADVERSE REACTIONS: In the literature no side effects or adverse reactions are documented.
DRUG INTERACTIONS OR OTHER: As it is a non ionic molecule, triclosan is compatible with mouthrinse or dentifrices formulations, thus it does not display any drug interaction of other kind.
ALTERATIONS TO LABORATORY RESULTS: There are no reports displaying any alteration of laboratory tests.
CARCINOGENESIS, MUTAGENESIS, TERATOGENESIS AND FERTILITY PRECAUTIONS: There are no reports proving any effects on carcinogenesis, mutagenesis, teratogenesis and/or fertility alterations.
DOSE AND ADMINISTRATION, MANNER OF USE:
MOUTHRINSE NEDENTO · TRICLOSAN. Use after eating and after dental brushing. Fill the measuring cup to the line (15 ml) and rinse the mouth without diluting for 30-60 seconds, twice or thrice a day.
Allow for the mouthrinse to be in contact with the whole oral surface, specially between the teeth. Do not water rinse after application. Do not eat or drink nor use tobacco-based products for the next 30 minutes after use. Topical use.
TOOTHPASTE NEDENTO · TRICLOSAN: brush the teeth and gums thoroughly 3 times a day, after each meal for 3 minutes. Do not eat or drink or use any tobacco-based products for the next 30 minutes after use. Topical use.
DEMONSTRATION AND OVER DOSIFICATION OR ACCIDENTAL INGESTION MANAGEMENT:
Even if the product is topically applied, hypersensitive reactions can happen, including anaphylactic shock, which is rare and not frequent. It is recommended to stop treatment and seek for medical advice. If overdosification or accidental ingestion happens seek for medical advice.
MOUTHRINSE NEDENTO · TRICLOSAN: 300ml bottle of 0.15% solution of Triclosan with Vitamin B5, Allantoin and sodium fluoride with measuring cup.
TOOTHPASTE NEDENTO · TRICLOSAN 75 ml tube of 0.30% Triclosan with Vitamin B5, Allantoin and sodium fluoride.
STORAGE: Keep at room temperature and in a dry and cool place.
PROTECTIVE LEGENDS: Keep out of the reach of children. Do not use during pregnancy and breastfeeding. Exclusive literature for dentists and doctors. If any discomfort or unpleasant sensation is present during treatment with MOUTHRINSE NEDENTO · TRICLOSAN and/or TOOTHPASTE NEDENTO · TRICLOSAN, seek for medical advice. NEDENTO is a registered trademark.
MOUTHRINSE NEDENTO · TRICLOSAN 300 ml bottle.
TOOTHPASTE NEDENTO · TRICLOSAN 75 ml tube.